The EDAIC Part 1 Syllabus, Broken Down by Subject

Paper A: Basic Sciences

Anatomy

Anatomy questions focus on applied, clinically relevant knowledge. Expect questions on:

Airway anatomy — larynx, trachea, bronchial tree, relations of the recurrent laryngeal nerves.
Neuraxial anatomy — vertebral column, spinal cord, meninges, dermatomes, blood supply.
Vascular anatomy — major vessels, anatomical relations for central venous access (internal jugular, subclavian, femoral), arterial cannulation sites.
Peripheral nerve anatomy — brachial plexus, lumbar plexus, sciatic nerve, relevant surface landmarks and relations for regional blocks.
Thoracic and abdominal anatomy — diaphragm, mediastinum, relations of major organs.

High-yield areas include airway structures, the spine and spinal cord, and the anatomy underpinning common regional techniques. Cross-sectional imaging (CT, MRI slices) occasionally appears; familiarity with axial anatomy at key levels (e.g. C6, T4, L3) is useful.

Physiology

Physiology is heavily weighted in Paper A and integrates closely with clinical scenarios. Core topics:

Cardiovascular physiology — cardiac cycle, pressure–volume loops, determinants of cardiac output, coronary circulation, baroreceptor reflexes, regional circulations (cerebral, renal, uteroplacental).
Respiratory physiology — mechanics of breathing, lung volumes and capacities, ventilation–perfusion relationships, gas exchange, oxygen and carbon dioxide transport, control of breathing, hypoxic pulmonary vasoconstriction.
Renal physiology — glomerular filtration, tubular function, regulation of sodium, potassium, water and acid–base balance.
Acid–base physiology — buffer systems, respiratory and metabolic compensation, interpretation of blood gases.
Neurophysiology — action potentials, synaptic transmission, autonomic nervous system, cerebral blood flow and intracranial pressure, pain pathways.
Endocrine and metabolic physiology — glucose homeostasis, thyroid, adrenal and pituitary function, calcium regulation, stress response to surgery.
Haematology and coagulation — clotting cascade, platelet function, fibrinolysis, transfusion physiology.
Maternal and neonatal physiology — physiological changes of pregnancy, placental transfer, fetal circulation, transition at birth.

Physiology questions often present a clinical context (e.g. haemorrhage, one-lung ventilation, pregnancy) and test your understanding of the underlying mechanisms. Graphs and diagrams (oxygen–haemoglobin dissociation curve, compliance curves, renal handling of substances) are common.

Pharmacology

Pharmacology spans general principles and specific drug classes:

Pharmacokinetics — absorption, distribution, metabolism, excretion; volume of distribution, clearance, half-life, bioavailability; context-sensitive half-time.
Pharmacodynamics — receptor theory, agonists and antagonists, dose–response curves, potency and efficacy.
Intravenous anaesthetics — propofol, thiopental, etomidate, ketamine.
Volatile anaesthetics — MAC, uptake and distribution, effects on organ systems.
Opioids — morphine, fentanyl, alfentanil, remifentanil; pharmacology and side effects.
Neuromuscular blocking drugs — depolarising and non-depolarising agents, monitoring, reversal.
Local anaesthetics — mechanism of action, structure–activity relationships, systemic toxicity, maximum safe doses.
Cardiovascular drugs — inotropes, vasopressors, antihypertensives, antiarrhythmics.
Drugs acting on the respiratory system — bronchodilators, pulmonary vasodilators.
Anticoagulants and antiplatelet agents — heparin, warfarin, direct oral anticoagulants, aspirin, clopidogrel.
Antibiotics, antiemetics, and other adjuncts relevant to perioperative care.

Questions may ask about mechanisms, side effects, drug interactions, or the rationale for dose adjustment in renal or hepatic impairment. Understanding both the principles and the specifics of commonly used drugs is essential.

Physics and Clinical Measurement

This subject covers the physical principles underlying monitoring and equipment:

Principles of measurement — accuracy, precision, calibration, sources of error.
Pressure measurement — invasive (transducers, zeroing, damping) and non-invasive (oscillometry).
Gas laws — Boyle's, Charles's, Gay-Lussac's, ideal gas equation, Dalton's and Henry's laws.
Oxygen measurement — pulse oximetry (Beer–Lambert law, sources of error), oxygen analysers (paramagnetic, fuel cell, Clark electrode).
Capnography — infrared absorption, waveform interpretation, causes of abnormal traces.
Electrical safety — mains supply, earthing, isolated circuits, microshock and macroshock, diathermy.
Ultrasound — basic physics, Doppler effect, applications in anaesthesia.
Temperature measurement — thermistors, thermocouples, infrared.
Vaporisers — plenum and draw-over, temperature and pressure compensation.
Breathing systems — Mapleson classification, fresh gas flow requirements, circle systems, CO₂ absorption.

Physics questions often include diagrams or waveforms. A solid grasp of the underlying principles — rather than rote memorisation — will help you tackle novel scenarios.

Statistics

Statistics is a smaller but important component:

Descriptive statistics — mean, median, mode, standard deviation, variance, normal distribution.
Study design — randomised controlled trials, cohort studies, case–control studies, blinding, bias, confounding.
Hypothesis testing — null hypothesis, p-values, Type I and Type II errors, confidence intervals.
Common statistical tests — t-test, chi-squared test, ANOVA, correlation and regression.
Sensitivity, specificity, positive and negative predictive values — interpretation of diagnostic tests.
Meta-analysis and systematic reviews — basic concepts.

Statistics questions may present study data or a clinical scenario and ask you to interpret results or identify the appropriate test. Familiarity with the language of evidence-based medicine is valuable across both papers.

Paper B: Clinical Anaesthesia and Intensive Care

General Principles of Anaesthesia

Preoperative assessment — risk stratification, ASA classification, consent, fasting guidelines.
Airway management — assessment, basic and advanced techniques, difficult airway algorithms, complications.
Induction, maintenance, and emergence — choice of technique, monitoring, common problems.
Fluid therapy — crystalloids, colloids, blood products, goal-directed therapy.
Perioperative complications — hypotension, hypertension, arrhythmias, hypoxia, bronchospasm, anaphylaxis.

Sub-Specialty Anaesthesia

Paper B covers anaesthesia for a wide range of surgical specialties:

Cardiac and thoracic anaesthesia — coronary artery disease, valvular disease, one-lung ventilation, post-operative care.
Neurosurgery and neuroanaesthesia — raised intracranial pressure, cerebral perfusion, positioning, awake craniotomy.
Obstetric anaesthesia — labour analgesia, caesarean section (regional and general techniques), maternal complications (haemorrhage, pre-eclampsia), neonatal resuscitation.
Paediatric anaesthesia — physiological differences, consent, induction techniques, fluid management, common procedures.
Trauma and emergency anaesthesia — rapid sequence induction, haemorrhage control, damage-control surgery.
ENT, maxillofacial, and ophthalmic anaesthesia — shared airway, laser safety, intraocular pressure.
Orthopaedic and plastic surgery — regional techniques, tourniquets, fat embolism.
Urology, general surgery, and day-case anaesthesia — specific considerations for common procedures.

Regional Anaesthesia

Neuraxial blocks — spinal and epidural anaesthesia, combined spinal–epidural, contraindications, complications (high block, local anaesthetic toxicity, epidural haematoma).
Peripheral nerve blocks — upper limb (interscalene, supraclavicular, axillary), lower limb (femoral, sciatic, popliteal, ankle), truncal blocks (transversus abdominis plane, rectus sheath).
Ultrasound guidance — principles, advantages, safety.

Regional anaesthesia questions often integrate anatomy, pharmacology, and clinical decision-making.

Intensive Care Medicine

Respiratory failure and mechanical ventilation — modes of ventilation, weaning, acute respiratory distress syndrome (ARDS), ventilator-associated pneumonia.
Cardiovascular support — shock (cardiogenic, septic, hypovolaemic), inotropes and vasopressors, fluid resuscitation.
Renal failure — acute kidney injury, indications for renal replacement therapy, modalities (intermittent haemodialysis, continuous haemofiltration).
Neurological critical care — traumatic brain injury, subarachnoid haemorrhage, status epilepticus, sedation and analgesia, delirium.
Sepsis and infection — definitions, source control, antimicrobial therapy, sepsis bundles.
Nutrition — enteral and parenteral feeding, metabolic support.
End-of-life care — withdrawal of treatment, brainstem death testing, organ donation.

Intensive care is a substantial component of Paper B and reflects the breadth of ICU practice.

Emergency Medicine and Resuscitation

Advanced Life Support (ALS) — cardiac arrest algorithms, peri-arrest arrhythmias, post-resuscitation care.
Trauma management — ATLS principles, primary and secondary survey, airway management in trauma, haemorrhage control.
Acute medical emergencies — anaphylaxis, acute coronary syndromes, pulmonary embolism, acute asthma, diabetic emergencies.

Questions often present time-critical scenarios and test your knowledge of structured approaches and guidelines.

Pain Management

Acute pain — multimodal analgesia, patient-controlled analgesia (PCA), epidural analgesia, peripheral nerve catheters.
Chronic pain — neuropathic pain, cancer pain, interventional techniques.
Pharmacology of analgesics — opioids, NSAIDs, paracetamol, adjuvants (gabapentinoids, antidepressants).

Pain management integrates pharmacology, physiology (pain pathways), and clinical practice.

High-Yield Areas and Weighting

While the EDAIC does not publish exact question breakdowns, certain subjects consistently appear more frequently:

Physiology and pharmacology are the largest components of Paper A.
Cardiovascular, respiratory, and neuraxial topics are perennially high-yield across both papers.
Obstetric anaesthesia, paediatric anaesthesia, and intensive care are substantial in Paper B.
Regional anaesthesia integrates anatomy, pharmacology, and clinical technique and is a common focus.

Less heavily weighted but still important: statistics, physics (though equipment and monitoring are clinically relevant), and some sub-specialties (e.g. ENT, urology) appear less often but are part of the syllabus.

Exam tip: The official ESAIC syllabus document lists learning objectives for each topic. Use it as a checklist: if a topic is on the syllabus, it is fair game. Prioritise breadth first — cover the entire syllabus at a foundational level — then deepen your knowledge in high-yield areas.

Planning Your Study

Download the official syllabus from the ESAIC/EDAIC website and familiarise yourself with its structure.
Map your resources — textbooks, review courses, question banks — to the syllabus headings. Standard texts cover most topics; EDAIC study material and question banks (such as those on AnesCORE) are designed to mirror the exam format and content.
Allocate time by subject weight — spend more hours on physiology, pharmacology, and core clinical topics than on niche areas.
Integrate basic science with clinical context — understanding why (physiology, pharmacology) helps you answer how (clinical management) questions in Paper B.
Practise MTF questions regularly — the format rewards precise knowledge and the ability to evaluate independent statements. Familiarity with question style is as important as content knowledge.
Revise iteratively — multiple passes through the syllabus, each time adding depth, are more effective than a single exhaustive read-through.

Key point: The EDAIC syllabus is broad, but it is finite and well-defined. Systematic coverage, guided by the official document and supported by high-quality EDAIC study material, is the most reliable path to success.

Frequently Asked Questions

What is the official EDAIC syllabus and where can I find it?

The official syllabus is a detailed document published by ESAIC (the European Society of Anaesthesiology and Intensive Care) listing all topics and learning objectives for the EDAIC Part 1 examination. You can download the current version from the ESAIC/EDAIC website under the "Examinations" or "EDAIC" section.

How much of the EDAIC Part 1 exam is basic science versus clinical?

Paper A is entirely basic science (anatomy, physiology, pharmacology, physics, statistics), while Paper B is clinical (anaesthesia, intensive care, pain, emergency medicine). Both papers carry equal weight, so roughly half the exam is basic science and half is clinical, though clinical questions in Paper B often require applied basic science knowledge.

Which subjects should I prioritise when studying the EDAIC syllabus?

Physiology and pharmacology are the most heavily weighted in Paper A. In Paper B, cardiovascular and respiratory anaesthesia, obstetric and paediatric anaesthesia, regional anaesthesia, and intensive care medicine are consistently high-yield. However, the syllabus is broad, so aim for comprehensive coverage and then focus extra time on these core areas.

Can I pass EDAIC Part 1 by studying only high-yield topics?

No. While some subjects appear more frequently, questions can come from any part of the syllabus. A candidate who neglects lower-weighted topics risks missing marks that could make the difference between pass and fail. The most successful strategy is broad, systematic coverage of the entire EDAIC syllabus, supported by targeted revision of high-yield areas and regular practice with MTF questions.

Final Thoughts

The EDAIC Part 1 syllabus is comprehensive, spanning the foundational sciences and the full breadth of anaesthetic and intensive care practice. Breaking it down subject by subject — and understanding the weighting and interconnections — allows you to study strategically and efficiently. Use the official syllabus as your roadmap, integrate your learning across basic science and clinical contexts, and practise consistently with exam-style questions. With a structured approach and the right resources, the syllabus becomes manageable and success achievable.

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